Ways to create probe groups

A probe group is a collection of probes associated by a set of logical criteria, and serves as a required building block for a microarray design. A single microarray design can contain probes for thousands of different targets, so placing these probes into logical groups simplifies the data sets, and subsequently the process of creating a microarray design.

• Create new probe group using an existing probe group - This method is useful if there is an existing probe group in eArray that contains most or all of the probes that you want in your new probe group. You first search for the existing probe group and make a copy of it. Then you can make edits to the copy.

• Create new probe group by uploading probes - In this method, you first upload your probe sequence into eArray. At the end of the upload process, you can create a new probe group that contains the uploaded probes.

• Create new probe group using a High Density (HD) search - This method is best if all the probes you want to include in the group can be found in a high-density probe search.

• Create new probe group using a SNP probe search - This method is specifically for creating a group of SNP probes that will be part of a CGH+SNP microarray.

• Create new probe group using GE probe design - With this method, you use the probes generated by a GE probe design job to create a probe group. It is the best approach if you want eArray to design your probes based on target sequences.

• Create new probe group using Genomic Tiling - This method is available in the CGH, ChIP, and SureSelect Capture Array application types. It creates a probe group from probes that span defined genomic intervals at even intervals.

• Create new probe group using probe search results - Use this method to create probe groups from probes that are returned in a search (Search Standard Probes or GO Search). You first perform the search, then select the probes of interest to create a group.

• Create new probe group using Simple Tiling - This method is available in the Expression application type. It creates a probe group from probes that span uploaded target sequences at even intervals.